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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d96122ce0e2395e1a4785658e4828f09567f4351b636e1427220aa5e64ccee6' 
  AND token = 'CtNj9+FxpQvxyZDlSfs68zTyYIqO6btyVHWt4WQTsEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}