SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f132e8b6a2d792483d2d0200d6546fdda55a73ae568644ecf20aaf51de5709d' 
  AND token = 'qrj87pMKeTLB/me7Esgcv27g8gZWPz/kdnrsM3Si3mE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}