SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d03bb1022acd8faae5c64233d8a64964728ea4c4d8b63d48c23418b024b2300' 
  AND token = '5J4nTRjv4S1eWM5UsBzJO+PXy5kqK1wVtEjduImUD3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}