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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a3a532b5d137bfa8ade8ed62a8760b0a2e500278dc9e843d955ff6164393a5f' 
  AND token = 'p2D921n2DzgmwlNqta+Ma9r3MRq1Tv/seClamFRW1Og=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}