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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd580d3ffe2e20dda1d876fef58f28e4585edd97f5928a32473d23ae8882c14d3' 
  AND token = '0OfxCcwiLCnuy0SQxuwR14n/4+mKJumIzRGKWldgWLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}