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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edaea52655807385306a9f42a72e211226f2f3c7b464b8810e81e00a8d9052c0' 
  AND token = 'IxwOehHGbBPi+uOdj0vrm/ro/7WCSIKEFR0jVaHVz5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}