SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ca7ca05fa3dd0d4d548e62ffcf34ece49413b2171995f76bd24676cd68f7add' 
  AND token = 'TFP/iuIvTuimPQsVpgxD8ohcuKOi4rwrf4S0hJTdjao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}