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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '118905eba6526dcafba9527b9f47a87347c6d1ae8a48f76a95906f2d8733430a' 
  AND token = 'nVrIdZL+01+neHgGc9rON7T3mZhE6ks7uOQ9PYDhM4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}