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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b97cda9a886c2e887c9c71c85330418b22625c98b20ab945a4276860498c9b0a' 
  AND token = 'sTfx6btgGniuigqGhNKlvoz3TkcgyZchr9Hxv9WbxOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}