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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7db411ec867eac674692f9cc3fd15a04b7bed14f4f95569e35f419bd4b2689e1' 
  AND token = 'XP0wQp+gd9c2/FdrM2LNKFYfWnG1BGtezF0VZgy67Fw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}