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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1497b7f1ceb305877064923b267e56d1fd60d0dee6767c787c4e4b6a9b39564' 
  AND token = 'JvUDI+Doh54pr7q8vo6N8v03nsGrKNknqTfNqHS7AZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}