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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd60e9f77ceedee85b02091c32a7e895e014309ec5fdf7e2f1c6292fe09dc2fb7' 
  AND token = 'vXjO4BxPE+4uM3GfrLjyCXCquTcRpSlVIfDUmckOvjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}