SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9700c50b49007cf8fe2bdabbc4f5252e83a06bde849005937905d26cbc43adb' 
  AND token = 'cQMsAFt9oN26POvDg0KejyMrwUNCZnc72mcG7gA4HAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}