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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '595001db8ea9e510a1574844f1e4a9eb48625a7c53754e85fe195ea72c62c9cf' 
  AND token = 'KLfjLN+JicDwy/4W5ZiAJrgEtoiAps2v7Um/Uz/GaDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}