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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d85047395f92db4ccbf841e6c257af2bec249e2e3c73ad4442f23841d458439' 
  AND token = 'G+UqOkfNsWt5yVlfHyvr2bMBVcEBtYPd0gq5T6ZCXAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}