SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '506e26f7939c8d7e2031573993d6951595bfac932b77bdea2f80fc3116da898c' 
  AND token = 'MHM0rsUjgM+dWGmyu9ofNIVuCu2owmNZFn36xynOXyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}