SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '601e4ca8e9a430f1f453ccfb133a651efd54a613b2045a0bf5c8d061bb819f23' 
  AND token = '6VhjHxSqU1TUp6qBIWK2xpRvYdXY0KMMW85KcOAx7mY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}