SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48c8feaeba3aa33dcaa7cd5a6effe93f72a9d9f54c8442abb9849be1a51c9370' 
  AND token = 'Oobyws5NOw8ZmqbWDGTZLa3aedTD3vGZ0iJJLFJ/9UM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}