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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b1f25b00e43fd84f97f2843b607e70d9bc9d993a6003b25066c188c5879b2ef' 
  AND token = 'nTceMNSSVXVqAEFMtbhGcnLgUIPbWP8PCmlUazk18ec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}