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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01511ffc4cca505b8eae1e669d81c9bb0e7004ad4be5a897b5065b1eeffde633' 
  AND token = '0XmhafpHLpQcwTR90lMRKY/3m0GueWQnVliYsyokmJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}