SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad50ef66d6e09be3fd38bffef7a9960add15ec0f551ee0a1efa36ec135773296' 
  AND token = 'kxH1E0gzvZx12X6D6h9ew7cdskSczEPQ5/5ILDVBGXQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}