SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca86fbb08f8a7ccae59c013e3fc03c270098e0ce77109fc1642e014f2e269978' 
  AND token = 'ov7m2Cln1MxISHNUpI28yRrDCRh0bsyKanCWBy0YRUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}