SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37e07b5a6ce626ad64158fec42d7863fda9480e132410e18aec27cf97a2dac00' 
  AND token = 'aP+2jV1BAaa2OQ0cQyJllOqpKNMiXCeUyIhj42sCEW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}