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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40ab44ed3ab96bb93ab2992f1c9c8d190ca6013dc159b7f04040a268df703d08' 
  AND token = 'hlWTR2gvorJ/GMAG5UXtKrpX4IdCkAfOTrxnE6aLduo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}