SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c66feb54ced036989d5ae0aa559d28434459deb9b7618c689446bded6653145' 
  AND token = 'rLoxE4SMCNPLutyqM02+eIuyNxE5oG+Ai75R8CqANSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}