SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78f557e5970770ecf0885e74f7cb4ceadb01afb7cf08febeb85c38c6e4986a09' 
  AND token = '37x9Dj6X/pj4aKj+5hTszt0rSw3HygkB+gEKY0oNw28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}