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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de12d0aba4ce59e67acb41f5c8255dfcb8bd10e0d8acb6a06c8928170e185a5a' 
  AND token = 'X7pETXgun0prFHXDi7sa6lQj18Gv3q5N/0DXJs+t8HE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}