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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ad67d46070e3ccdcd0894116d0c3068405621fc40450503069da84b68f82b0e' 
  AND token = '0EHXINOUFNb+ZlLgbmMsEuATP52+oVQmFUiuMFKVnLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}