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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fad7d2d20ca4426aabdb421018e188e4a9c745f5871a2ab845b7580ee20463cb' 
  AND token = 'Pk//It7T//WkhSMzwvXp2eOgHNz3EBK9/B07tCgMtTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}