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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6328101583441d67d65856107221eeef5a820966bf8bd1baac306ee29b8390bf' 
  AND token = 'S0j8zTUl/bGBiyVmc2UqGnjA9EXxGr+BTV90YokxcMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}