SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4d88426dc0439529d816868b6d1e1fa7e06d5e2506a81e359393e924eb2c724' 
  AND token = '2CUBALVdQ/oWI3qenhQ1t9RP7weJr/+3v06Leq7JlM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}