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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60d9ab5fe56a776fbcbd344b89841e9289f354e1750b0debe0c8f0e946b2c458' 
  AND token = 'P0E57BbRp0mic9+4mJid51a2aDZmQQe66yapU+y0iPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}