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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2601601dff900d76304cd139f16ba394dc75ff01f4910e6831d33935a7014d88' 
  AND token = 'Nq/fpKvY3UFtP5P8nr0duXMx8xczfwjVezlnke51RXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}