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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53dcd1dbbce0422cbf6d34d6bc02762376177939e0691f25c803f98fd195b4c0' 
  AND token = 'G0qwLrRw8MCZNV2Ww+Y4ug2CVy9kw1rGqGtgLFEK5b4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}