SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fe9e5623637810d021686f199c6efba99c3ef63ecc332e37d5002aab221c6b2' 
  AND token = 'QmiA4venVRsxJdq2SU6eNJPxHXkdEZ+WQ9VD/FA9R04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}