SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b149c0bc44d0a8f32cae47b0a93ce65947046bc3b0b76c6babec9228e47ee245' 
  AND token = 'SBFpTSlDDSvn+Qe1/QlUeMtKCcOcPeELtiNm6JnEJAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}