SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5a262bbfdf3c0ee3f2df5ab1745e786e9b15b3fc4368ce33b03715f759f6544' 
  AND token = 'XZT58tOOzgCVpmG6OnEUuspva8iwPGsByazmpuZEifE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}