SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1406ac86a9a67af85a601e39c96ad0cf5aab6ee00674b3ad9bf0f9f98affe49f' 
  AND token = 'DWgIWaobY6RanKzbn8VzkCsbLUJqzmu4QDgN0R9eezE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}