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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51d631e1551c0ea52c11311d0c71b8965ed750402fe98ec5597989066481f8f1' 
  AND token = 'Qy1t0dMxPYVa8bA+NYIF6JRgxJt9Hb50x8m0UAweIN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}