SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '223619623e286e504eacd59209c915e6f8ff7f170a2e1bbb4932a35354c2281d' 
  AND token = 'MnZ5nvcOIOmy7IKETaAYr0Gnr7Zum3RkLFh+6fOR34k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}