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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b4ac5709019a692f4a73ce74e9b49db7bf75fac4aa135accd4410e5d82f1c83' 
  AND token = '+zMMI+53XGT9cb/U9BAePVU8PcZlU+L7rQaHcfCHSK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}