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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ab11fb957a2dd95f8700dd59b80e56f4fef8855b99a9af42608d2413c341f9d' 
  AND token = 'rS8zbhEX9+O2+E8s9APWQ+Ro3nNaw8aKuaDfyw4RbLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}