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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06b2ab407e48726d28f9764b910057feb000bd0ee4a9179c6b95f8d53ebdfdcf' 
  AND token = 'SIy+QVLHSxgTYxH4k6rQfSFFcQHhiY5ffqDZd7MpeeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}