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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f888d98c4ba0b74eba70450ad28cdc07b5e08d40174933ebdbc5e227e3b131ac' 
  AND token = 'B1PZC5rjI0PQu+nIt/8xm3lkSGiRndnt3Cg+ertIBW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}