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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec42e7fea1a328d6a277a14e0c69369715ea35e83114837ffbc0f9f9cb0f0324' 
  AND token = 'baX45a9FknDtOlCS8TMRPha8md1MnYuiZS8cXzW0nN8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}