SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cfa922ef64ff5fa57694412e3025cac5f279aa42a18f70cc687fa232a237647' 
  AND token = 'zfBCAIAEjKzJ/l9XNDK76tSe4pABO7knPAWmpNrZmCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}