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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a94e90a86e50ec4b4381e7e37c4d6680872e83afa011d158704063edf770bb3d' 
  AND token = 'iGjTeUhPFLmRx+dcWb54X1V77ER/tTw+ci4bv3AtPRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}