SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc3606a20918654b4afc11712f90067c7d54f82fb0433a48ff62751f10404ca9' 
  AND token = 'AnxuOLWmdEXaxh7m5nd3ulHrB7vY7p5MeUTtQ0vcfV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}