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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f061e351dc2f0183b3e0ee8ce3e071d1f89720eb36c5b31da2e1401239f6911' 
  AND token = 'UY7mmuZD3BL/RGRCYbq3kptKUykhn0Sy1Xhy0lf8JdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}