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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e016afe9562ed69a89e5e0164295a91739ee3ddcb29ff9288ad25b0dcda05d5' 
  AND token = 'Frj1aUDb7KDJ81BGjJJutZwxxWGM83TOKpmFt3d9g6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}